For best results start seed indoors, 4 weeks prior to the last frost. Sow 2-3 seeds 1⁄2 inches deep in 21⁄4 inches Jiffy strips. Provide a warm soil temperature (24-27 degrees C) and even moisture. Cucamelons are slow starters, especially compared to cucumbers. They need more time to germinate and can take as long as 3-4 weeks to germinate.
Transplant outdoors after all risk of frost has passed, space plants 6 inches apart in rows 4-6 feet apart. Cucamelons require a bright, warm growing season of about 3 months duration. Row covers or black mulch are highly recommended for extending growing season, to ensure maturity and to increase yield.
Full sun and sheltered location with soil pH of 6.0-7.0. As they are heavy feeders, an application of compost or well-rotted manure worked into the planting area will help. Regular applications of a complete soluble fertilizer during the growing season is beneficial. Plants should not be allowed to wilt. Make sure they are well-watered before transplanting.
Keep mature cucamelons picked off the vines to encourage a longer yield.
Monitor for Cucumber beetles; use Rotenone to control beetles. Leaf spots and mildew can be controlled using a sulfur or copper fungicide.